:root {
  /* background */
  --c-dark: #363435;
  --c-light: #ffffff;
  --c-accent: #e91d2e;

  /* text */
  --txt-c-dark: var(--c-dark);
  --txt-c-light: var(--c-light);
  --txt-c-accent: var(--c-accent);

  /* font */
  --font-main: "Open Sans", sans-serif;

  /* container width */
  --vertical-scroll: 20px;
  --mobile: calc(300px + var(--vertical-scroll));
  --tablet: calc(640px + var(--vertical-scroll));
  --desktop: calc(900px + var(--vertical-scroll));
  --desktop-lg: calc(1270px + var(--vertical-scroll));

  /* animation */
  --animation-fast: 0.1s;
  --animation-slow: 0.3s;
  --animation-transition: all 0.3s ease-in-out;
}

html {
  /* scroll-behavior: smooth; */
}

body {
  font-family: var(--font-main);
  color: var(--txt-c-dark);
  background-color: var(--c-light);
}
.helper-center {
  width: 2px;
  height: 210vh;
  position: fixed;
  transform: translate(0, -50%);
  left: 50%;
  border-left: 1px dotted #000;
  z-index: 10;
}

.container {
  width: 1300px;
  margin: 0 auto;
  z-index: 1;
  position: relative;
  text-align: center;
 
  
  /* border-left: 1px dotted #000;
  border-right: 1px dotted #000; */
}
.wrapper {
  width: 100%;
  position: relative;
  z-index: 1;
  overflow: hidden;
}

/* HEADER */
.header {
  height: 98px;
  display: flex;
  align-items: center;
  width: 100%;
  position: fixed;
  top: 0;
  left: 0;
  z-index: 2;
  background-color:rgba(255, 255, 255, 0);
  box-shadow: 0px 0px 10px 0px rgba(0, 0, 0, 0);
  transition: var(--animation-transition);
}
.header.fix_header{
  background-color:rgba(255, 255, 255, 1);
  box-shadow: 0px 0px 10px 0px rgba(0, 0, 0, 0.5);
}
.menu-items {
  left: 0;
  width: 100%;
  display: flex;
  align-items: center;
  justify-content: space-between;
}
.menu-item {
  background: var(--c-accent);
  color: var(--txt-c-light);
  text-decoration: none;
  font-size: 28px;
  font-weight: 700;
  padding: 6px 30px 10px 30px;
  border-radius: 50px;
}
.logo-menu {
  background: none;
  padding: 0;
  margin: 0;
  opacity: 0;
  transition: var(--animation-transition);
}
.header.fix_header .logo-menu{
  opacity: 1;
}
/* MAIN SCREEN */

.main-title {
  font-size: 54px;
  margin: 0;
  width: 93%;
  color: var(--txt-c-light);
  text-align: center;
  position: relative;
  display: block;
  text-shadow: 0 0 20px rgb(0 0 0 / 50%);
}
.main-title:after{
  /* content: '';
  width: 100%;
  height: 700px;
  position: absolute;
  transform: translate(-50%, -50%);
  top: 50%;
  left: 50%;
  z-index: 0;
  background-image: url(/img/bg_txt.png);
  background-repeat: no-repeat;
  background-size: contain; */
}
.main-descr {
  font-size: 34px;
  font-weight: 600;
  margin-bottom: 55px;
}
.main-btn {
  display: inline-block;
  box-sizing: border-box;
  font-size: 20px;
  font-weight: 600;
  color: #44423e;
  text-decoration: none;
  padding: 13px 67px;
  border-radius: 50px;
  background: #ffffff;
  margin-left: 40px;
  box-shadow: 0px 0px 10px 0px rgba(0, 0, 0, 0.3);
  transition: var(--animation-transition);
}
.header.fix_header .main-btn{
  background-color: #d4191f;
  color: #ffffff;
}
.main-btn:hover{
  transform: scale(1.05);
}
.main-links{
  display: flex;
  flex-direction: row;
  align-items: baseline;
}
.instr-btn {
  margin-top: 20px;
  display: inline-block;
  box-sizing: border-box;
  font-size: 26px;
  color: var(--txt-c-dark);
  border: 2px solid var(--c-dark);
  text-decoration: none;
  padding: 15px 80px;
  border-radius: 50px;
  position: relative;
  overflow: hidden;
  transition: var(--animation-transition);
}
.instr-btn span{
  width: 100%;
  height: 100%;
  position: absolute;
  opacity: 0;
  top: 0;
  left: 0;
  z-index: -1;
  background: rgb(231, 6, 40);
  background: -moz-linear-gradient(
    0deg,
    rgba(231, 6, 40, 1) 0%,
    rgba(227, 123, 12, 1) 80%
  );
  background: -webkit-linear-gradient(
    0deg,
    rgba(231, 6, 40, 1) 0%,
    rgba(227, 123, 12, 1) 80%
  );
  background: linear-gradient(
    0deg,
    rgba(231, 6, 40, 1) 0%,
    rgba(227, 123, 12, 1) 80%
  );
  filter: progid:DXImageTransform.Microsoft.gradient(startColorstr="#e70628",endColorstr="#e37b0c",GradientType=1);
  transition: var(--animation-transition);
}
.instr-btn:hover{
  color: var(--txt-c-light);
  border: 2px solid transparent;
}
.instr-btn:hover span{
opacity: 1;
}
.main-screen {
  height: 100vh;
  background-image: url('/img/bg.jpg');
  background-size: cover;
  background-position: center center;
  background-repeat: no-repeat;
  display: flex;
  align-items: flex-end;
}

.main-screen .container {
  display: flex;
  align-items: center;
  z-index: 2;
  height: 100%;
}
.main-screen-center {
  margin-right: 30px;
  margin-top: 100px;
}
.main-screen-left {
  margin-bottom: 18vh;
  width: 50%;
  display: flex;
  flex-direction: column;
  align-items: center;
}
.main-screen-right-item {
  color: var(--txt-c-light);
  display: flex;
  align-items: center;
}
.right-item-icon {
  margin-right: 30px;
}
.right-item-title {
  font-size: 21px;
  font-weight: 700;
}
.right-item-descr {
  font-size: 18px;
}

.right-des-img {
  position: absolute;
  top: -170px;
  left: -160px;
  width: 1170px;
}
.main-screen-right {
  position: relative;
  height: 100%;
  top: 100px;
}
.main-screen-right-items {
  position: relative;
  z-index: 2;
}
.main-screen-right-des {
  position: absolute;
  width: 50%;
  top: 0;
  right: 0;
  z-index: 1;
}
.main-screen-img {
  margin-top: 7vh;
 max-width: 629px;
 width: 100%;
  height: auto;
}
.right-item-info {
  width: 310px;
}
.main-screen-right-item {
  position: absolute;
  top: 0;
  left: 0;
}
.main-screen-right-item:nth-child(1) {
  margin: -40px 0px 0 -180px;
}
.main-screen-right-item:nth-child(2) {
  margin: 80px 0px 0 -30px;
}
.main-screen-right-item:nth-child(3) {
  margin: 220px 0px 0 20px;
}
.main-screen-right-item:nth-child(4) {
  margin: 380px 0px 0 10px;
}
.main-screen-right-item:nth-child(5) {
  margin: 530px 0px 0 -40px;
}



.custom-btn {
  width: 187px;
  height: 58px;
  color: #fff;
  
  border-radius: 5px;
  font-family: var(--font-main);
  /* font-family: 'Lato', sans-serif; */
  font-size: 20px;
  font-weight: 700;
  background: transparent;
  cursor: pointer;
  transition: all 0.3s ease;
  position: relative;
  display: inline-block; 
  padding: 10px 25px;
   box-shadow:inset 2px 2px 2px 0px rgba(255,255,255,.5),
   7px 7px 20px 0px rgba(0,0,0,.1),
   4px 4px 5px 0px rgba(0,0,0,.1);
  outline: none;
}
.btn-7 {
	/* background (204,0,51); */
   background: linear-gradient(0deg, rgba(204,0,51,1) 0%, rgba(251,75,2,1) 100%);
  line-height: 42px;
  padding: 0;
  border: none;
  margin-right: 30px;
 }
.btn-7 span {
  position: relative;
  display: flex;
  align-items: center;
  justify-content: center;
  width: 100%;
  height: 100%;

}
.btn-7:before,
.btn-7:after {
  position: absolute;
  content: "";
  right: 0;
  bottom: 0;
  background: rgba(251,75,2,1);
  box-shadow:
   -7px -7px 20px 0px rgba(255,255,255,.9),
   -4px -4px 5px 0px rgba(255,255,255,.9),
   7px 7px 20px 0px rgba(0,0,0,.2),
   4px 4px 5px 0px rgba(0,0,0,.3);
  transition: all 0.3s ease;
 
}
.btn-7:before{
   height: 0%;
   width: 2px;
}
.btn-7:after {
  width: 0%;
  height: 2px;
}
.btn-7:hover{
  color: rgba(251,75,2,1);
  background: transparent;

}
.btn-7:hover:before {
  height: 100%;
  
}
.btn-7:hover:after {
  width: 100%;
  
}
.btn-7 span:before,
.btn-7 span:after {
  position: absolute;
  content: "";
  left: 0;
  top: 0;
  background: rgba(251,75,2,1);
  box-shadow:
   -7px -7px 20px 0px rgba(255,255,255,.9),
   -4px -4px 5px 0px rgba(255,255,255,.9),
   7px 7px 20px 0px rgba(0,0,0,.2),
   4px 4px 5px 0px rgba(0,0,0,.3);
  transition: all 0.3s ease;
}
.btn-7 span:before {
  width: 2px;
  height: 0%;
}
.btn-7 span:after {
  height: 2px;
  width: 0%;
}
.btn-7 span:hover:before {
  height: 100%;
}
.btn-7 span:hover:after {
  width: 100%;
}

/* MAIN */
.main-video-container {
  width: 100%;
  height: auto;
  overflow: hidden;
  position: relative;
  display: flex;
  align-items: center;
}

.main-play-btn {
  display: block;
  width: 120px;

  height: 120px;
  display: flex;
  align-items: center;
  justify-content: center;
  position: absolute;
  background: var(--c-accent);
  z-index: 2;
  border-radius: 100px;
  box-shadow: 2px 3px 10px 0px rgba(0, 0, 0, 0.5);
  cursor: pointer;
  transform: translate(-50%, -50%) scale(1);
  top: 40%;
  left: 50%;
  opacity: 1;
  transition: var(--animation-transition);
}
.main-play-icon {
  margin-left: 10px;
  width: 40px;
}
.main-video {
  display: block;
  width: 1070px;
  height: 587px;
  padding: 100px 0;
  position: relative;
  margin: 0 auto;
}
.main-video-content {
  width: 100%;
  height: 100%;
  position: relative;
  box-shadow: 0 0 15px 1px rgba(0, 0, 0, 0.27);
}

.main-video-container.video-active .main-bg {
  opacity: 0;
}
.main-video-container.video-active .main-play-btn {
  transform: translate(-50%, -50%) scale(0.7);
  left: 10%;
  opacity: 0.5;
}
/* COMBI */
.effects.selectcomb{
  background-color: #f8f5f3;
  padding-bottom: 100px;
}
.effects.selectcomb .effects-title{
  margin: 0 0 80px 0;
  padding-top: 100px; 
}
.combicenter-left-img{
  max-width: 570px;
  width: 100%;
  height: auto;
}
.combicenter{
  display: flex;
  flex-direction: row;
}
.combicenter-left, .combicenter-right{
  width: 50%;
  display: flex; 
}
.combicenter-left{
  justify-content: center;
  align-items: center;
}
.combicenter-left img{
  margin: 30px 0 0 0;
}
.combicenter-right{
  justify-content: center;
}
.combicenter-right ul{
  margin: 0 0 0 30px;
  padding: 0;
}
.combicenter-right ul li{
  cursor: pointer;
  list-style-type: none;
  padding: 0;
  display: flex;
  flex-direction: row;
  align-items: center;
  height: 109px;
  padding-right: 70px;
  width: 410px;
  background-color: #ffffff;
  margin: 25px 0;
  border-radius: 100px;
  box-shadow: 0px 0px 10px 0px rgba(0, 0, 0, 0);
  transition: var(--animation-transition);
}
.combicenter-right ul li:hover{
  box-shadow: 0px 0px 10px 0px rgba(0, 0, 0, 0.5);
}
.combicenter-right img{
  margin-right: 30px;
  margin-left: -1px;
}
.combicenter-right p{
  font-size: 22px;
}


/* EFFECTS */
.effects {
  padding-bottom: 100px;
  background-color: #ffe6c9;
}
.effects-title {
  font-size: 36px;
  font-weight: 700;
  text-align: center;
  margin: 0;
  padding-top: 50px;
}
.effects-items .swiper-wrapper {
  flex-direction: row;
  align-items: flex-end;
}
.swiper-container {
  width: 100%;
  height: 100%;
  margin-left: auto;
  margin-right: auto;
}
.swiper-container.effects-items {
  overflow: visible;
  width: 100%;
}

.swiper-slide {
  text-align: center;
  font-size: 18px;
  background: transparent;
  height: calc((100% - 30px) / 2);

  /* Center slide text vertically */
  display: -webkit-box;
  display: -ms-flexbox;
  display: -webkit-flex;
  display: flex;
  -webkit-box-pack: center;
  -ms-flex-pack: center;
  -webkit-justify-content: center;
  justify-content: center;
  -webkit-box-align: center;
  -ms-flex-align: center;
  -webkit-align-items: center;
  align-items: center;
}

.effects-item {
  background: var(--c-light);
  width: 300px;
  height: 340px;
  display: flex;
  flex-direction: column;
  align-items: center;
  justify-content: center;
  box-shadow: 0 0 15px 1px rgba(0, 0, 0, 0);
  transition: var(--animation-transition);
  cursor: pointer;
}
.effects-item:hover{
  box-shadow: 0 0 15px 1px rgba(0, 0, 0, 0.27);
}
.effects-des {
  position: absolute;
  top: 70px;
  left: -160px;
}
.effects-des-img {
  position: absolute;
  margin: 40px 0 0 -280px;
}

.swiper-button-prev,
.swiper-button-next,
.swiper-pagination {
  display: none;
}

/* WHERE */
.where {
  padding-top: 75px;
  background-color: #ffe6c9;
  padding-bottom: 50px;
}
.where-title {
  font-size: 36px;
  font-weight: 700;
  text-align: center;
  margin: 0 0 55px 0;
}

/* compendium */
#comp_wgt {
  height: 685px;
  width: 100% !important;
}
.selected-drug > .clearfix .description .drug-forms {
  max-height: none;
}
#comp_wgt .tab-pane {
  height: 524px !important;
}
#comp_wgt .balloon-wrapper .balloon-content {
  border: 3px solid var(--c-accent);
}
#comp_wgt .balloon-wrapper .balloon-content .buy-btn-container .icn-buy-btn {
  background: var(--c-accent);
}

/* FOOTER */
.footer {
  padding-top: 75px;
}
.hw-img {
  width: 100%;
  height: auto;
  margin-bottom: 35px;
}
.ligal{
  color: #b2b2b2;
  font-size: 18px;
  text-align: center;
  margin: 0 0 50px 0;
}

/* MEDIA  1490 */
@media only screen and (max-width: 1400px) {
  .container {
    width: 1000px;
    padding: 0 12px;
    box-sizing: border-box;
	text-align: center;
  }
  .main-title {
    font-size: 35px;
  }
  .main-descr {
    font-size: 21px;
  }
  .main-screen-img {

  }
  .main-btn, .instr-btn {
    font-size: 16px;
  }
  .right-item-icon-img {
    width: 82px;
    height: 82px;
  }
  .right-item-icon {
    margin-right: 20px;
  }
  .right-item-title {
    font-size: 14px;
  }
  .right-item-descr {
    font-size: 12px;
  }
  .main-screen-right-item:nth-child(1) {
    margin: -10px 0px 0 -130px;
  }
  .main-screen-right-item:nth-child(2) {
    margin: 90px 0px 0 -50px;
  }
  .main-screen-right-item:nth-child(3) {
    margin: 200px 0px 0 0px;
  }
  .main-screen-right-item:nth-child(4) {
    margin: 310px 0px 0 -20px;
  }
  .main-screen-right-item:nth-child(5) {
    margin: 430px 0px 0 -40px;
  }
  .right-des-img {
    top: -100px;
    left: -130px;
    height: 800px;
  }
  .main-video {
    display: block;
    width: 970px;
    height: 534px;
    position: relative;
    margin: 0 auto;
  }
  .effects-des-im {
    width: 240px;
  }
  .effects-des {
    position: absolute;
    top: 0px;
    left: -160px;
  }
  .effects {
    padding-bottom: 30px;
  }
  .swiper-container.effects-items {
    width: 970px;
  }
  .effects-item {
    width: 300px;
    height: 210px;
  }
  .effects-title {
    font-size: 30px;
    font-weight: 700;
    text-align: center;
    margin: 0px 0 30px 0;
  }
  .effects-img {
    width: 80px;
  }
  .where {
    padding-top: 45px;
  }
  .where-title {
    font-size: 30px;
  }
  #comp_wgt {
    height: 435px;
  }
  #comp_wgt .tab-pane {
    height: 273px !important;
}
.header {
  height: 72px;
}
}


@media only screen and (max-width: 1000px) {
  .container {
    width: 320px;
  }
  .logo-menu-img{
    display: none;
  }
  #comp_wgt {
    height: 417px;
}
  .main-btn{
    margin: 0;
    font-size: 14px;
    padding: 9px 27px;
  }
  .main-links {
    display: flex;
    flex-direction: row;
    align-items: center;
    width: 100%;
    justify-content: space-around;
}
  .header {
    height: 50px;
  }
  .menu-items {
    top: 15px;
  }
  .logo-menu-img {
    width: 140px;
  }
  .main-screen {
    /* height: 500px;
    background-position-x: 80%; */
    background-image: url(/img/bg_mob.jpg);
  }
  .main-title{
    font-size: 30px;
  }
  .main-screen-left{
    width: 100%;
  }
  .main-screen .container {
    flex-direction: column;
    justify-content: flex-start;
  }
  .main-screen-left {
    margin-top: 9vh;
    margin-bottom: 0;
  }
  .main-screen-img {
    width: 270px;
    margin-top: 4vh;
  }
  .main-screen-center {
    order: 1;
    margin: 0;
  }
  .main-screen-right {
    order: 3;
    margin-top: 20px;
  }
  .main-descr {
    text-align: center;
    margin-bottom: 10px;
  }
  .main-screen-right-item {
    color: var(--txt-c-dark);
  }
  .right-item-info {
    width: auto;
  }
  .main-screen-right-items .main-screen-right-item {
    margin: 0;
    position: relative;
  }
  .main-screen-right-items {
    margin: -40px 0 0 0;
}
.effects.selectcomb .effects-title {
  margin: 0px 0 40px 0;
  padding-top: 70px;
}
.effects.selectcomb {
  padding-bottom: 50px;
}
.combicenter{
  flex-direction: column;
}
.combicenter-left, .combicenter-right{
  width: 100%;
}
.combicenter-right ul{
  margin: 0;
}
.combicenter-right p {
  font-size: 18px;
}
.combicenter-right img {
  width: 90px;
  margin-right: 15px;
}
.combicenter-right ul li{
padding-right: 30px;
height: 88px;
    width: 100%;
    box-sizing: border-box;
}
  .right-des-img {
    top: -20px;
    left: -20px;
    height: 430px;
    width: 490px;
  }
  .main-video-container {
    height: auto;
    padding: 0;
    margin-top: 0;
  }
  .main-play-btn {
    width: 60px;
    height: 60px;
  }
  .main-play-icon {
    width: 23px;
  }
  .main-video {
    width: 320px;
    height: 176px;
  }
  .effects-title {
    font-size: 24px;
    z-index: 2;
    position: relative;
  }
  .effects-des {
    left: -70px;
    z-index: 1;
    top: 60px;
  }
  .effects-item {
    margin: 15px;
  }
  .effects-des-im {
    width: 130px;
  }
  .swiper-container.effects-items {
    width: 100%;
    z-index: 2;
    overflow: hidden;
    padding-bottom: 30px;
  }
  .swiper-button-prev,
  .swiper-button-next,
  .swiper-pagination {
    display: block;
  }
  .swiper-button-next:after,
  .swiper-button-prev:after {
    font-size: 22px;
    color: var(--txt-c-accent);
  }
  .swiper-pagination-bullet-active {
    background: var(--c-accent);
  }
  .swiper-button-next {
    top: 45%;
    display: flex;
    right: 15px;
    outline: none;
  }
  .swiper-button-prev {
    top: 45%;
    display: flex;
    left: 15px;
    outline: none;
  }
  .where-title {
    font-size: 24px;
    margin-bottom: 30px;
  }
  #comp_wgt .tab-pane {
    height: 219px !important;
  }
  .footer {
    padding-top: 45px;
  }
  .hw-img {
    margin-bottom: 15px;
  }
  .ligal {
    font-size: 10px;
  }
}